The downfall of this compound is the little amount of real scientific research available simply because big pharma has no use for this compound. Meaning not a single person has a clue of what long term use of this product could do.
Personally, I would prefer to have my body's natural estrogen present doing very predictable and calculated actions rather than an insect steroid that no one can tell what happens long term. Compounds that claim to increase muscle mass and physical performance are always going to seem attractive. A huge tell-tell sign of if a compound is worth taking or not is seeing WHO is talking about it. If a salesman of turkesterone is telling you amazing things, well no surprise! It is their job to generate revenue, not influence what is best for you.